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"Human microbiome is now recognized as a central player in human health, and the oral microbiome is of increasing significance in human biology. The oral cavity includes several microbial habitats and is the central channel for entry of bacteria into the human body. It constitutes the second most complex ecological system in [the] human body after the gut microbiome."
Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients. npj Biofilms and Microbiomesvolume 2, Article number: 7 (2016)